BREAKTHROUGH SCIENCE

9 Years of research, inspired by bone repair technology have led to the development of the exclusive and clinically proven NR-5™ technology.

The Breakthrough Technology – NR-5™

Years of international research in our laboratories inspired by advanced bone repair technology, have led to the development of the exclusive and internationally patented NR-5™ technology. The international research team identified two NR-5™ ingredients – calcium silicate and sodium phosphate – which combine to form a crystal structure that is identical to what tooth enamel is made of, specifically, Hydroxyapatite, the key mineral in dental enamel.

The Breakthrough Technology – NR-5™

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Clinically Proven

NR-5™ technology was developed in partnership with dentists and experts from the International Oral Care Centres. A series of scientific studies have been carried out at Unilever R&D laboratories in Shanghai and Port Sunlight. These studies demonstrated the ability of REGENERATE Enamel Science™ Advanced Toothpaste and Advanced Enamel Serum to promote tooth enamel mineral regeneration.

Clinically Proven

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9 years of research

REGENERATE Enamel Science™ is the first and only oral care regime with NR-5™ proven to form hydroxyapatite directly onto teeth surface, with identical composition to the underlying tooth enamel mineral. Our patented NR-5™ technology regenerates 82% of enamel mineral after three days¹.Clinically proven and scientifically tested, REGENERATE™ was developed by Unilever Oral Care scientists in collaboration with dentists from international oral health centres and with:

- Intertek Clinical Research Services, United Kingdom
- Modus laboratories Ltd, United Kingdom
- Therametric Technologies, Inc, United States
- SICCAS Shanghai Institute of Ceramics, Chinese Academy of Science

¹Based on an in vitro test measuring enamel surface microhardness after 3 days’ combined use of Advanced Toothpaste and Advanced Enamel Serum
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9 years of research

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